Aline Azabdaftari

Abstract The proximal part of the small intestine, including duodenum and jejunum, is not only dedicated to nutrient digestion and absorption but is also a highly regulated immune site exposed to environmental factors. Host-protective responses against pathogens and tolerance to food antigens are essential functions in the small intestine. The cellular ecology and molecular pathways to maintain those functions are complex.

Aline Azabdaftari https://orcid.org/0000-0002-1597-0486 and Holm H. Uhlig Abstract REFERENCES AND NOTES Abstract New data suggest how epithelial dysfunction and intestinal dysbiosis contribute to inflammatory bowel disease in patients and in models of XIAP deficiency (see the related Research Articles by Strigli et al. and Wahilda et al.). Get full access to this article View all available purchase options and get full access to this article. Already a Subscriber?Sign In REFERENCES AND NOTES 1 R.