Allison Alwan TerBusha on Muck Rack

Allison Alwan TerBusha

As seen in: American Society for Microbiology (ASM)
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Articles

A Kaposi's Sarcoma-Associated Herpesvirus Infection Mechanism Is Independent of Integrins α3β1, αVβ3, and αVβ5

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By Allison Alwan TerBusha, Hee Jun Leea, Allison Alwan TerBush, Florianne Hafkamp
| American Society for Microbiology (ASM)
Host receptor usage by Kaposi's sarcoma-associated herpesvirus (KSHV) has been best studied using primary microvascular endothelial and fibroblast cells, although the virus infects a wide variety of cell types in culture and in natural infections. In these two infection models, KSHV adheres to the cell though heparan sulfate (HS) binding and then interacts with a complex of EphA2, xCT, and integrins α3β1, αVβ3, and αVβ5 to catalyze viral entry.
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