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Allitia DiBernardo

As seen in: Color Research & Application, NeurologyLive
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Articles

Substance use disorders and risk for treatment resistant depression: a population‐based, nested case-control study

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By Philip Brenner, Lena R Brandt, Janssen Research, Allitia DiBernardo
| Color Research & Application Verified
Abstract Background and aims Treatment‐resistant depression (TRD), defined as inadequate treatment response after at least two adequate treatment trials, is common among patients initiating antidepressant treatment. Current or previous substance use disorders (SUD) are common among patients with depression and often lead to worse treatment outcomes. However, in clinical studies, SUD have not been found to increase the risk for TRD.
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Treatment‐resistant depression as risk factor for substance use disorders-a nation‐wide register‐based cohort study

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By Philip Brenner, Lena R Brandt, Janssen Research, Allitia DiBernardo
| Wiley Online Library Verified
Abstract Background and aims Treatment‐resistant depression (TRD) is common among patients with major depressive disorder (MDD). MDD may increase the risk for developing substance use disorders (SUD). The aim of this study was to investigate the risk for developing SUD among patients with TRD compared with other depressed patients. Design Observational cohort study. Setting Nation‐wide governmental health registers in Sweden.
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