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Alloysius Gomez

As seen in: BioRxiv
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Articles

Time-course Transcriptomics Reveals the Impact of Treponema pallidum on Microvascular Endothelial Cell Function and Phenotype

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By Sean M Waugh, Mara C. Goodyear, Alloysius Gomez, Akash Ranasinghe
| BioRxiv
Abstract Syphilis, caused by Treponema pallidum subsp. pallidum, is an urgent global public health threat. Syphilis vaccine development has been impeded by limited understanding of the molecular mechanisms that enable T. pallidum to establish and maintain infection. The vascular endothelium is critical for T. pallidum attachment, dissemination, and host immune response initiation; however, the molecular details of T. pallidum-endothelial interactions are incompletely understood.
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In-Depth Proteome Coverage of In Vitro-Cultured Treponema pallidum and Quantitative Comparison Analyses with In Vivo-Grown Treponemes

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By Simon Houston, Andrew Geppert, Alloysius Gomez, Mara C. Goodyear
| dx.doi.org
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Proteome Res. 2024, XXXX, XXX Simon Houston Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8P 5C2, Canada , Alloysius Gomez Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8P 5C2, Canada , Andrew Geppert Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8P 5C2, Canada , Mara C.
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