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Almedina Redzematovic on Muck Rack

Almedina Redzematovic

As seen in: European Urology
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Articles

Tumor Xenografts of Human Clear Cell Renal Cell Carcinoma But Not Corresponding Cell Lines Recapitulate Clinical Response to Sunitinib: Feasibility of Using Biopsy Samples - European Urology

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By Brandon Manley, Almedina Redzematovic, Yiyu Dong, Maria F. Becerra
| European Urology Verified
Parallel development of preclinical models that recapitulate treatment response observed in patients is central to the advancement of personalized medicine. To evaluate the use of biopsy specimens to develop patient-derived xenografts and the use of corresponding cell lines from renal cell carcinoma (RCC) tumors for the assessment of histopathology, genomics, and treatment response.
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Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma

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By Brandon Manley, Emily C. Zabor, Jozefina Casuscelli, Daniel M. Tennenbaum, Almedina Redzematovic
| European Urology Verified
Analyses of associations between clinicopathologic outcomes and recurrent somatic mutations in clear cell renal cell carcinoma (ccRCC) have been limited to individual cohorts. To define clinicopathologic associations between specific mutations and ccRCC disease characteristics. DNA sequencing data were pooled from three collaborative genomic cohorts (n = 754) and our institutional database (n = 295). All patients had clinical data and identification of somatic mutations from their primary tumors.
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