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Whole‐exome sequencing for genetic diagnosis of idiopathic liver injury in children
1 INTRODUCTION Childhood liver disorders can be upon a variety of internal and external culprits including infections, drugs and toxins, metabolic disorders, autoimmunity and malignancy, with severity of injury ranging from mild, transient elevations in liver enzymes to severe hepatic failure.1-7 Affected children with poorly functioning liver may need prolonged treatment and/or transplantation, or even die.
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