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Spaceflight-induced changes in white matter hyperintensity burden in astronauts

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By Noam Alperin, Ahmet Bagci, Sang Lee, Alperin Noninvasive Diagnostics
| Neurology Verified
Objective: To assess the effect of weightlessness and the respective roles of CSF and vascular fluid on changes in white matter hyperintensity (WMH) burden in astronauts. Methods: We analyzed prespaceflight and postspaceflight brain MRI scans from 17 astronauts, 10 who flew a long-duration mission on the International Space Station (ISS) and 7 who flew a short-duration mission on the Space Shuttle.
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