Alun Hughes

1 INTRODUCTION The most important difference between blood flow in the arteries and the more familiar fluid flow in pipes and ducts is that the arteries are deformable. The pressure that drives the flow also deforms the arteries in which the blood is flowing and this must be taken into account when analysing the flow. The effect is particularly important when the flow is unsteady; and arterial flow is intrinsically unsteady due to its pulsatile nature.

Abstract APOE genotype is a very strong genetic risk factor for late-onset Alzheimer’s disease (AD). This relationship may involve mediation by common infections—several of which are also dementia risk factors. We investigated associations of APOE ε2 and ε4 carriage with serostatus and antibody titres to 14 common pathogens in three population-based cohorts (UK Biobank, National Survey of Health and Development, Southall and Brent Revisited).

POLICY Call for tourism tax to help reverse austerity The introduction of a tourist tax would help reverse austerity’s ‘heavy toll’ on councils, the Autonomy Institute think-tank has claimed. By Izzy Lepone | 06 August 2025 SHARE © Balate.Dorin/Shutterstock The introduction of a tourist tax would help reverse austerity's ‘heavy toll' on councils, the Autonomy Institute think-tank has claimed.