Alun Hughes

Abstract APOE genotype is a very strong genetic risk factor for late-onset Alzheimer’s disease (AD). This relationship may involve mediation by common infections—several of which are also dementia risk factors. We investigated associations of APOE ε2 and ε4 carriage with serostatus and antibody titres to 14 common pathogens in three population-based cohorts (UK Biobank, National Survey of Health and Development, Southall and Brent Revisited).

POLICY Call for tourism tax to help reverse austerity The introduction of a tourist tax would help reverse austerity’s ‘heavy toll’ on councils, the Autonomy Institute think-tank has claimed. By Izzy Lepone | 06 August 2025 SHARE © Balate.Dorin/Shutterstock The introduction of a tourist tax would help reverse austerity's ‘heavy toll' on councils, the Autonomy Institute think-tank has claimed.

FISCAL DEVOLUTION On the right path to fiscal devo Government accepts the fiscal devolution principle, says Alun Hughes, and he argues that a County Councils' Network report shows why ministers now need to empower local leaders. By Alun Hughes | 16 July 2025 SHARE Turbocharged! World-Class!! A Revolution!!! It is almost a pre-requisite these days for a government press release to ramp up the rhetoric. Usually it is a case of don't believe the hype.