Amal Robay on Muck Rack

Amal Robay

As seen in: Nature
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Articles

Impact of population-specific pharmacogenomic variants on drug dosing in ICU patients

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By Mahboubeh Rostami, Juan L Rodriguez-Flores, Huda Khan, Edin Karic, Jason G. Mezey, Amal Robay, Ronald G. Crystal, Ali Ait Hssain, Alya Al Shakaki, Muneera Vakayil, Maha Elhamid
| Nature Verified
Abstract Intensive care units (ICU) patients are highly vulnerable to inaccurate drug dosing. Pharmacogenomics (PGx) studies the role of inherited genetic variation in drug metabolism and dose efficacy.
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Copy number variations in the genome of the Qatari population

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By Khalid A Fakhro, Noha A Yousri, Juan L Rodriguez-Flores, Amal Robay, Michelle R Staudt
| Biomed Central (BMC)
To identify CNVs in the Qatari population, primary data was obtained from arrays and whole-genome sequencing sources, and then called and integrated as described in methods (Fig. 1). Briefly, CNV calls were first generated in the 100 individuals from Illumina’s Omni2.5 M array intensity data using both cnvPartition (Illumina’s proprietary Beadstudio plug-in) and QuantiSNP [27], and, separately, from NGS using cn.MOPS [28], in addition to CNV calls provided by Illumina from WGS data.
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