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Ambar Delgado on Muck Rack

Ambar Delgado

As seen in: BioRxiv, eLife, The Seahawk
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Articles

Ca2+ channel and active zone protein abundance intersects with input-specific synapse organization to shape functional synaptic diversity

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By Audrey T. Medeiros, Scott J. Gratz, Ambar Delgado, Jason T Ritt
| eLife
eLife assessment Calcium channels are key regulators of synaptic strength and plasticity. The authors generate new endogenous tags of the Drosophila channel Cac as well as auxiliary subunits to investigate distinct calcium channel functions at the fly NMJ, Is and Ib. They demonstrate functions for voltage-gated calcium channel subunits in promoting synaptic strength, diversity, and plasticity with a series of convincing analyses. The work is important and has broad implications.
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Ca2+ channel and active zone protein abundance intersects with input-specific synapse organization to shape functional synaptic diversity

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By Audrey T. Medeiros, Scott J. Gratz, Ambar Delgado, Jason T Ritt
| BioRxiv
Abstract Synaptic heterogeneity is a hallmark of nervous systems that enables complex and adaptable communication in neural circuits. To understand circuit function, it is thus critical to determine the factors that contribute to the functional diversity of synapses.
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Molecular and organizational diversity intersect to generate functional synaptic heterogeneity within and between excitatory neuronal subtypes

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By Audrey T. Medeiros, Scott J. Gratz, Ambar Delgado, Jason T Ritt
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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