Amezcua Vesely

Introduction IL-17A and IL-17F were initially associated with the pathogenesis of autoinflammatory and autoimmune disorders (1). Nonetheless, the primary function of these cytokines is likely host protection against microbes. Indeed, mice deficient in IL-17A and/or IL-17F are highly susceptible to infection with a wide array of fungi and extracellular bacteria, as well as viruses and parasites (2, 3).