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Amirhossein Davari on Muck Rack

Amirhossein Davari

As seen in: Nature
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Articles

Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during Candida albicans immunosurveillance

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By Nicolas Millet, Jinendiran Sekar, Norma Solis, Jian Miao, Antoine Millet, Asia S. Wildeman, Melissa Cook, Brian Peters, Michail S Lionakis, Sarah Gaffen, Nicholas G. Jendzjowsky, Scott G. Filler, Marc Swidergall, Felix E. Y. Aggor, Amirhossein Davari
| Nature Verified
Abstract Mucosal barrier integrity is vital for homeostasis with commensal organisms while preventing pathogen invasion. Here we show that fungal-induced immunosurveillance enhances resistance to fungal outgrowth and tissue invasion by remodeling the oral mucosal epithelial barrier in mouse models of adult and neonatal Candida albicans colonization.
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