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Amparo Roig Adam

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Articles

Developmentally dynamic, non-convergent transcriptomic profiles in CNV models for schizophrenia risk

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By Shuyang Yao, Lisa Bast, Paul Stümpges, Fatima Memic, Jennifer G Mulle, Patrick Sullivan, Jens Hjerling-Leffler, Hayley French, Amparo Roig Adam
| Nature Verified
Abstract Schizophrenia is a complex psychiatric disorder with significant genetic and clinical heterogeneity. Although numerous rare copy number variations (CNVs) with high risk for schizophrenia have been identified, they show no obvious overlap in gene content or function. We hypothesized that the downstream effects of schizophrenia-associated CNVs converge on shared molecular pathways.
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