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Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV

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By Jessica Davidson, Raghav Jain, Thomas Kizzar, Gisela Geoghegan, Daniel Nesbitt, Amy Cavanagh, Akira Abe, Kwamina Nyame, Andrea Hunger, Xiaojuan Chao, Isabella James, Helaina Walesewicz, Dominique Baldwin, Gina Wade, Sylwia Michorowska, Rakesh Verma, Kathryn L. Schueler, Vania Hinkovska-Galcheva, Evgenia Shishkova, Wen-Xing Ding, Joshua Coon, James A. Shayman, Monther Abu-Remaileh, Judith Simcox, Gina Wade, Rakesh Ver
| Cell Metabolism Verified
Keywords lysosome lipidomics liver cold exposure liquid chromatography-mass spectrometry LC-MS transcription factor EB TFEB phospholipase A2 G15 Pla2g15 bis(monoacylglycero)phosphate BMP Introduction The liver maintains energy homeostasis in mammals by acting as a metabolic transistor switching between providing glucose or lipids for peripheral tissue catabolism. In the fed state, the liver is a sink for excess glucose to maintain normoglycemia.
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Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV

|
By Jessica Davidson, Raghav Jain, Thomas Kizzar, Gisela Geoghegan, Daniel Nesbitt, Amy Cavanagh, Akira Abe, Kwamina Nyame, Andrea Hunger, Isabella James, Dominique Baldwin, Gina Wade, Sylwia Michorowska, Rakesh Verma, Kathryn L. Schueler, Vania Hinkovska-Galcheva, Evgenia Shishkova, Wen-Xing Ding, Joshua Coon, James A. Shayman, Monther Abu-Remaileh, Judith Simcox, Xiaojuan Chao, Helaina Walesewicz
| Cell Metabolism Verified
Keywords lysosome lipidomics liver cold exposure liquid chromatography-mass spectrometry LC-MS transcription factor EB TFEB phospholipase A2 G15 Pla2g15 bis(monoacylglycero)phosphate BMP Introduction The liver maintains energy homeostasis in mammals by acting as a metabolic transistor switching between providing glucose or lipids for peripheral tissue catabolism. In the fed state, the liver is a sink for excess glucose to maintain normoglycemia.
Open in Who Shared Issue with article?
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