Amy Jacob

Anastomotic leak (AL) is a feared complication of colorectal surgery, associated with high morbidity, mortality and adverse oncologic outcomes. Despite advances in perioperative care, its incidence remains significant, and prevention is a central challenge in modern colorectal practice. This review summarizes the current evidence on AL with a focus on risk factors, diagnostic considerations and preventive strategies.

Regeneron and Sanofi will continue marketing, manufacturing, and selling their PCSK9 inhibitor alirocumab (Praluent) in the United States after the US Court of Appeals for the Federal Circuit today suspended a lower court's injunction.In January, in a patent dispute, a judge had said the Regeneron had violated a patent held by its rival, Amgen's is evolocumab, marketed as Repatha.

During a dramatic nighttime ceremony live on television and Facebook, President Donald Trump announced Neil McGill Gorsuch, United States Circuit Judge of the United States Court of Appeals for the Tenth Circuit in Denver as his Supreme Court nominee, finally filling the ninth seat—a vacancy that has been under scrutiny since Justice Antonin Scalia’s death last February.In accepting the nomination, Gorsuch, introduced by Trump, pledged to fill the post with "impartiality, independence,...