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The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging
1 Introduction Frailty syndrome (FS) is a multidimensional clinical condition characterized by increased vulnerability to adverse health outcomes due to the cumulative decline in physiological reserve and function in older adults. Considering that FS is a heterogeneous syndrome, the standardization of a diagnostic method is challenging. It can be identified either through a physical phenotype (Fried et al.
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