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Anand Anbarasu on Muck Rack

Anand Anbarasu

As seen in: Nature, Wiley Online Library, Frontiers, BioRxiv
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Articles

Genomic and structural analysis of dacB variants associated with cephalosporin resistance in Pseudomonas aeruginosa

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By Tushar P Joshi, Vishnukumar Ramesh, Kamini Walia, Karthik Gunasekaran, Balaji Veeraraghavan, Sudha Ramaiah, Anand Anbarasu, Shalini Mathpal, Maruthan Karthik
| Nature Verified
Abstract The rise of resistance to fourth-generation cephalosporin in Pseudomonas aeruginosa (P. aeruginosa) is a global concern. The resistance is largely driven by variants of chromosomally encoded AmpC β-lactamase, known as Pseudomonas-derived cephalosporinase (PDC), which arise from the mutations in the ampC gene. In addition, alteration in dacB, which encode the penicillin-binding protein 4 (PBP4), can lead to the overexpression of ampC, thereby contributing to β-lactam resistance.
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In silico genomic analysis of resistome, virulome, and mobilome of β -lactamase-producing Klebsiella pneumoniae

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By Anand Anbarasu, Rhitam Biswas
| Nature Verified
Abstract Klebsiella pneumoniae (K. pneumoniae) is a major multidrug-resistant pathogen associated with nosocomial infections, particularly among immunocompromised patients, and contributes significantly to global morbidity and mortality. This study provides a comprehensive genomic analysis of β-lactamase-producing K. pneumoniae isolates.
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Genomic landscape of nosocomial Acinetobacter baumannii: A comprehensive analysis of the resistome, virulome, and mobilome - Scientific Reports

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By Anand Anbarasu
| Nature Verified
Abstract Acinetobacter baumannii (A. baumannii) is a major multidrug-resistant pathogen, posing serious threats in the healthcare settings. This study provides a comprehensive genomic analysis of nosocomial A. baumannii whole-genome sequences retrieved from NCBI Genome database. Multilocus sequence typing and capsule typing were performed to investigate the clonal diversity.
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