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Anantika Chandra

As seen in: Nature, MDPI, BioRxiv
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Articles

SARS-CoV-2 Delta variant-specific ORF3a mutations destabilize lysosomal homeostasis to trigger lysosomal damage-mediated cell death

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By Ayushi Amin Dey, Sanchita Mishra, Bharadwaj Vemparala, Anantika Chandra, Disha Jain, Narendra M. Dixit, Prasad Tammineni, Sannula Kesavardhana, Vigneshwar Reddy Ashireddygari
| Nature Verified
Abstract The variants of concern (VOCs) of SARS-CoV-2 emerged independently and became dominant globally at different times. Despite the emergence of multiple VOCs, the Delta variant of SARS-CoV-2 showed heightened pathogenicity and unprecedented mortality. However, the Delta variant specific mechanisms underlying its increased pathogenicity are unclear.
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PANoptosis Regulation in Reservoir Hosts of Zoonotic Viruses

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By Anantika Chandra, Sannula Kesavardhana
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Avian influenza virus neuraminidase stalk length and haemagglutinin glycosylation patterns reveal molecularly directed reassortment promoting the emergence of highly pathogenic clade 2.3.4.4b A (H5N1) viruses

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By Sannula Kesavardhana, Ranjana Nataraj, Anantika Chandra
| BioRxiv
Abstract The recently emerged panzootic clade 2.3.4.4b H5N1 influenza viruses show unprecedented extensive spread in wild birds and have been transmitted to several mammals, including humans. The virologic factors that have driven the success of the 2.3.4.4b H5N1 viruses, which has not been achieved by previous H5N1 clades, is unclear.
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