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Coculture to Vascularization Transition in Bioengineered Skin Grafts through VEGF-Associated Pathways Tracked by Exosomal Biomarkers
Coculture to Vascularization Transition in Bioengineered Skin Grafts through VEGF-Associated Pathways Tracked by Exosomal Biomarkers Inadequate vasculature poses a significant challenge in the clinical translation of tissue engineering constructs. Current strategies for vascularization typically recruit short-lived endothelial cells or induce mesenchymal stem cells (MSC) to differentiate into endothelial lineage, often in combination with supporting pericytes or fibroblasts.
A multiscale modeling to determine in vitro mechanical responses of different cells at the cell‐substrate interface under fluid perfusion
CONFLICT OF INTEREST STATEMENT The authors declare no potential conflict of interests. REFERENCES 1, , , . Controlling cell behavior through the design of polymer surfaces. Small. 2010; 6(20): 2208-2220. doi:10.1002/smll.201000233 2, , . Functional polymer surfaces for controlling cell behaviors. Mater Today. 2018; 21(1): 38-59. doi:10.1016/j.mattod.2017.07.002 3, , , , . Cell–substrate interactions. Princ Regen Med. 2019; 27: 437-468. doi:10.1016/B978-0-12-809880-6.00027-8 4, , , , .
Stiffness prediction on elastography images and neuro-fuzzy based segmentation for thyroid cancer detection
Abstract The elastography method detects metastatic changes by measuring the stiffness of tissues. Estimation of elasticities from elastography images facilitates more precise identification of the metastatic region and detection of the same. In this study, an automated segmentation algorithm is proposed that calculates pixel-wise elasticity values to detect thyroid cancer from elastography images.
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