Anders Aune Tveita on Muck Rack

Anders Aune Tveita

As seen in: Nature, Journal of Infection
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Articles

Targeting proteostasis in multiple myeloma through inhibition of LTK - Leukemia

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By Yannick Frey, Sigrid S. Skånland, Anders Aune Tveita, Kristine Misund, Lenka Besse, Kjetil Taskén, Fredrik Schjesvold, Thea Kristin Våtsveen, John Franklin Imbery
| Nature
Abstract Multiple myeloma (MM) cells secrete high levels of immunoglobulin and are therefore addicted to mechanisms that maintain proteome homeostasis (proteostasis). While proteasome inhibitors that target the degradative aspect of proteostasis have proven effective, only limited attempts have been made to target protein secretion.
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