Anders Boutrup Funch

ALDH aldehyde dehydrogenase DDTC diethyldithiocarbamate DDTC-ME methyl diethyldithiocarbamate dLN submandibular and cervical draining lymph nodes EBS European baseline series HPLC high-performance liquid chromatography OOA 1:4 mixture of olive oil:acetone RT room temperature TETD tetraethylthiuram disulfide ZDEC zinc diethyldithiocarbamate 1 INTRODUCTION Allergic contact dermatitis is a delayed hypersensitivity induced by exposure of the skin to contact allergens.

To the Editor, It is still a major question whether patients with atopic dermatitis (AD) have an altered response to contact allergens compared to controls without AD.1, 2 In an effort to address this question, we compared the response to the contact allergen 1-fluoro-2,4-dinitrobenzene (DNFB) in wild-type (WT), Flgft/ft and Tmem79ma/ma mice in a well-established model for allergic contact dermatitis (ACD).3 Flgft/ft and Tmem79ma/ma mice have defects in the skin barrier, but in contrast to...