Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
In this study, we systematically investigated the expression pattern and functional role of MAFF in NSCLC, elucidating its potential mechanisms in tumorigenesis and progression. Our results demonstrated that MAFF is significantly downregulated in NSCLC tissues, and its expression level strongly correlates with tumor angiogenesis. These findings provide novel insights into the potential of MAFF as a diagnostic biomarker and therapeutic target in NSCLC.
Clinical data and surgical specimens were retrospectively collected from 109 patients diagnosed with HCC at the Fourth Hospital of Hebei Medical University between November 2017 and January 2023. All patients had undergone curative surgical resection, and the presence of hepatocellular carcinoma was confirmed by postoperative pathology.
Discussion Immunotherapy is one important method for melanoma treatment, when alone or in combination with anti-PD-1 and anti-PD-L1 may improve survival rates (Simeone, Grimaldi & Ascierto, 2015). Nivolumab is a PD-1 inhibitor with high affinity to PD-1 (Hirano et al., 2005). However, the ineffectiveness or resistance of anti-PD-1 to melanoma is a serious problem.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
