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André D. Lopes

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Articles by André D. Lopes

Real-world evaluation of large language model for patients medical and administrative queries in nuclear medicine

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By Arash Latifoltojar, Akintunde T Orunmuyi, Michael Wang, Stefan Vöö, Irfan Kayani, Jennifer Williams, Memuna Rashid, Andre Romualdo Lopes, André D. Lopes, Ashley Groves, Jamshed Bomanji, Richard Oyibo, Kabita Gurung
| Nature Verified
Abstract Large language models (LLMs) may support patients by addressing their queries; however, their real-world clinical use remains uncertain. Patients’ queries prospectively collected and answered by nuclear medicine physicians, administrative staffs, and ChatGPT v4.1. Responses evaluated and Likert-scored by medical and administrative experts and two independent non-experts using 15 out of 17 dimensions of the proposed QUEST framework.
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Combined ctDNA and serum PSA for dynamic monitoring of metastatic prostate cancer starting first-line treatment: a prospective national cohort study

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By Anuradha Jayaram, Alison Reid, Francesco Orlando, Leila Zakka, Miriam Gonçalves, Constantine Alifrangis, Rob Jones Verified, Sarah H. Needleman, Diletta Bianchini, Anna Wingate, Kenrick Ng, Mark Linch, Ursula McGovern, John Staffurth, Simon J Crabb, Alison Birtle, Osvaldas Vainauskas, Gianmarco Leone, Allan Hackshaw, Andre Romualdo Lopes, André D. Lopes, Daniel Wetterskog, Francesca Demichelis, Gerhardt Attard, Memuna Rashid, Suparna Thakali, Jacqueline O’Dwyer, Elias Pintus, Susannah Brock, Millenn Chiwewe
| Nature Verified
Abstract The prognosis of newly diagnosed metastatic prostate cancer is highly variable. The primary objective of the PARADIGM prospective cohort study was to evaluate predictors of survival in blood collected at the start of each of the first six treatment cycles from 114 patients with high-volume metastatic prostate cancer (biologically male) who were starting androgen deprivation therapy in combination with docetaxel or an androgen receptor pathway inhibitor.
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Solid-state study of the structure and host-guest chemistry of cucurbituril-ferrocene inclusion complexes

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By Ana Gomes, Isabel Gonçalves, Martyn Pillinger, André D. Lopes
| Chemistry World Verified
Inclusion complexes of ferrocene (Fc) with cucurbit[n]urils (n = 7, 8) have been prepared via a rapid microwave-assisted hydrothermal approach. Solids were isolated and characterised by elemental analysis, powder X-ray diffraction (PXRD), spectroscopic, and thermoanalytical methods. The UV-Vis spectra support the presence of Fc in Fc@CB7 and a mixture of Fc and ferrocenium ions in Fc@CB8. Partial oxidation of Fc to Fc takes place in situ mainly due to the presence of acid of crystallisation in CB8.
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