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Andrea Saenz de Miera on Muck Rack

Andrea Saenz de Miera

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Articles

Concordance analysis of non-invasive techniques for PIK3CA and ESR1 mutations in advanced HR+/HER2- breast cancer: the CANIPE study

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By Ramón Manuel Lago-Lestón, Teresa Curiel, Carmela Rodriguez, Carmen Abuín, Patricia Pérez Palacios, Juan G Cueva, Marta Carmona, Alexandra Cortegoso, Serafín Morales, Josep Gumà, Mariana Lopez Flores Verified, Yolanda Fernandez, Isaura Fernández Pérez, Ignacio Fernández Sobrado, Maria Cortes Verified, Carolina Peña, Angel Díaz-Lagares, Laura Muinelo-Romay, Rafael López-López, Clotilde Costa, Aitor Rodríguez-Casanova, Alicia Abalo, Kepa Amillano, Jesús García-Mata, Andrea Saenz de Miera
| Nature Verified
Abstract Hormone receptor-positive (HR+) and HER2-negative (HER2−) breast cancer represents ~70% of breast tumors. Accurate detection of PIK3CA and ESR1 mutations is crucial for guiding targeted therapies, particularly in advanced disease. Liquid biopsy testing is increasingly recommended, especially for ESR1 mutation, but standardized genotyping methods remain limited. The CANIPE study, a prospective, multicenter Spanish trial, evaluated mutation prevalence in 106 baseline blood samples.
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