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Andreas Bjerregaard Kamstrup on Muck Rack

Andreas Bjerregaard Kamstrup

As seen in: Genome Medicine, BioRxiv, eLife
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Articles

circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

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By Andreas Bjerregaard Kamstrup, Morten Nielsen, Anne Kruse Hollensen, Mette Laugesen Graversgaard
| eLife
eLife assessment This work explores the role of one the most abundant circRNAs, circHIPK3, in bladder cancer cells, showing with convincing data that circHIPK3 depletion affects thousands of genes and that those downregulated (including STAT3) share an 11-mer motif with circHIPK3, corresponding to a binding site for IGF2BP2.
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circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

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By Andreas Bjerregaard Kamstrup, Morten Nielsen, Anne Kruse Hollensen, Mette Laugesen Graversgaard
| BioRxiv
Abstract Circular RNAs (circRNAs) represent a class of widespread endogenous RNAs that regulate gene expression and thereby influence cell biological decisions with implications for the pathogenesis of several diseases. Here, we disclose a novel gene-regulatory role of circHIPK3 by combining analyses of large genomics datasets and mechanistic cell biological follow-up experiments.
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Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

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By Shashank Sathe, Samuel Park, Andreas Bjerregaard Kamstrup, Asta Mannstaedt Rasmussen
| Genome Medicine Verified
ORCID: orcid.org/0000-0002-2779-40291,2, Shashank Sathe3, Samuel S. Park3, 4, 1,2, Archana Shankar3, Zong Ming Chua3, Niels Fristrup5, 1,2, Søren Vang1,2, Lars Dyrskjøt1,2, Stefan Aigner3, 4, Gene W.
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