Andreea Simona Covic

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This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessSystematic Review by 1,2,†, 2,3,†, 2,4,†, 2,3,*, 1,2, 1, 2,4 and 5,6 1 Nephrology Department, Dialysis and Renal Transplant Center, “Dr. C.I. Parhon” University Hospital, 700503 Iasi, Romania 2 Faculty of Medicine, “Grigore T. Popa” University of Medicine, 700115 Iasi, Romania 3 Department of Morpho-Functional Sciences I—Histology, Pathology, “Grigore T.

1. Introduction Recent high-level evidence confirms the superiority of transplantation in reducing all-cause mortality for most patients with end-stage kidney disease [1]. In the last decades, significant advances in the care of transplanted patients have led to massively improved 1 year graft survival [2]. However, long-term survival only slightly recorded improvement, highlighting the paramount importance of individualizing risk factors that alter the allograft health [3].