Andrew Charles co-corresponding on Muck Rack

Andrew Charles co-corresponding

As seen in: Oxford University Press (OUP)
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Articles

Effects of chronic caffeine on patterns of brain blood flow and behavior throughout the sleep-wake cycle in freely behaving mice

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By Yousef Yengej, Guido Faas, Kimiya Aframian, Andrew Charles co-corresponding
| Oxford University Press (OUP)
Caffeine has significant effects on neurovascular activity and behavior throughout the sleep-wake cycle. We used a minimally invasive microchip/video system to continuously record effects of caffeine in the drinking water of freely behaving mice. Chronic caffeine shifted both rest and active phases by up to 2 hours relative to the light-dark cycle in a dose-dependent fashion. There was a particular delay in onset of REM sleep as compared with non-REM sleep during the rest phase.
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