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Andrew Macpherson

As seen in: HuffPost, Nature, The Washington Post, Aol, AXS, Frontline Gastroenterology, South China Morning Post, Chron, Science Magazine, The Denver Post and
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Articles

Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation

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By Chiara Moretti, Estelle Grasset, Jiaying Zhu, Gaohua Yang, Louise E. Olofsson, Muhammad Khan, Per-Olof Bergh, Jee-Hwan Oh, Annika Lundqvist, Tom van Gils, Manuela Kramer, Lisa Olsson, Piyush Patel, Matthias Mitteregger, Daysi Espinola Monges, Chinmay Dwibedi, Kimberly A. Krautkramer, Nienke Koopman, Marcus Henricsson, Andrew Macpherson, Thue W. Schwartz, Gianfranco Grompone, Jan-Peter van Pijkeren, Valentina Tremaroli, Stefan Roos, Magnus Simrén, Fredrik Bäckhed
| Cell Reports Verified
Keywords gut microbiota serotonin tryptophan lactobacilli enteric nervous system irritable bowel syndrome Research topic(s) CP: Microbiology Introduction Serotonin (5-hydroxytryptamine; 5-HT) is a key signaling molecule in the intestine, mediating essential gastrointestinal (GI) functions, including peristalsis, vasodilation, and visceral sensitivity.1 Moreover, gut-derived serotonin is a trophic factor promoting the development and maintenance of the enteric nervous system (ENS),2,3 which...
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Diet-derived LPS determines intestinal IgA induction and repertoire characteristics independently of the microbiota

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By Catherine Mooser, Francesca Ronchi, Julien P. Limenitakis, Cristina Kalbermatter, Sandro Christensen, Tobias Fuhrer, Uwe Sauer, Andrew Macpherson, Stephanie Ganal-Vonarburg
| Cell Press Verified
Keywords diet lipopolysaccharide IgA germinal center B cells T follicular helper cells antibody repertoire GALT microbiota Introduction Body surfaces, such as the intestine, skin, female genital tract, and airways, are exposed to many different xenobiotic molecules. These include the metabolites from the microbiota, pathogenic toxins, and allergens. Foods are essential for calorie and micronutrient requirements, but dietary constituents or impurities can also act as allergens or immunogens.
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Andrew MacPherson | Christian Courier

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By Andrew Macpherson
| Christian Courier Verified
Skip to content I discovered NPR’s Tiny Desk series on YouTube a few years ago when I was obsessed with Snarky Puppy and striving to become a jazz musician. Live, unpolished performances without autotune or much prep time are the true test of accomplished artists. That is why when I chanced upon Maverick City Music’s Tiny Desk Concert,… We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits.
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