At the AACR Annual Meeting 2026, held April 17-22, National Cancer Institute (NCI) Director Anthony Letai, MD, PhD, FAACR, posed this question to attendees: “Where can you focus your efforts to make the cancer research system stronger, faster, and more effective for people with cancer?” Over the course of his address and fireside chat with AACR Immediate Past President Lillian L. Siu, MD, FAACR, and AACR President Keith T.