Andrzej Małecki

Abstract Obesity is a major global health concern, and sustained weight loss is often limited by increased appetite. The ketogenic diet (KD) has emerged as a potential appetite-modulating strategy. However, its neural and hormonal mechanisms remain incompletely understood. In this study, diet-induced obesity (DIO) was introduced to mice by 6-week Western chow feeding, followed by a 14-day KD intervention. Age-matched lean controls were maintained.

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Open AccessArticle by Katarzyna Zawiślak-Fornagiel 1, Daniel Ledwoń 2,*, Monika Bugdol 2, Patrycja Romaniszyn-Kania 2, Andrzej Małecki 3, Agnieszka Gorzkowska 4 and Andrzej W. Mitas 2 1 Department of Neurology, University Clinical Center Prof. K.