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Angika Bhasym on Muck Rack

Angika Bhasym

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Characterization of genetic predisposition and autoantibody profile in atypical haemolytic-uraemic syndrome

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By Savit Prabhu, Bahadur Singh Gurjar, Tholu Manikanta Sriharsha, Angika Bhasym
| Color Research & Application Verified
We previously reported that Indian paediatric patients with atypical haemolytic–uraemic syndrome (aHUS) showed high frequencies of anti‐complement factor H (FH) autoantibodies that are correlated with homozygous deletion of the genes for FH‐related proteins 1 and 3 (FHR1 and FHR3) (FHR1/3–/–). We now report that Indian paediatric aHUS patients without anti‐FH autoantibodies also showed modestly higher frequencies of the FHR1/3–/– genotype.
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