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Anirudhya Lahiri on Muck Rack

Anirudhya Lahiri

As seen in: Color Research & Application, Wiley Online Library
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Articles

Endoplasmic Reticulum Stress Amplifies Cytokine Responses in Astrocytes via a PERK/eIF2α/JAK1 Signaling Axis

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By Anirudhya Lahiri, Savannah Sims, Jessica A. Herstine, Alicia Meyer
| Wiley Online Library Verified
1 Introduction Neuroinflammation and dysregulation of proteostasis are hallmarks of numerous neurological disorders and may contribute to disease progression and pathology (Wilson III et al. 2023). Cells exposed to misfolded proteins, oxidative stress, and other neuropathological insults activate adaptive mechanisms to restore homeostasis. Central to this response is the attenuation of global protein synthesis via the integrated stress response (ISR).
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Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system

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By Neil T. Sprenkle, James W. Simpkins, Gordon P Meares, Anirudhya Lahiri
| Color Research & Application Verified
Corresponding Author E-mail address:gpmeares@hsc.wvu.edu Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, WV Rockefeller Neurosciences Institute, West Virginia University School of Medicine, Morgantown, WV Department of Neuroscience, West Virginia University School of Medicine, Morgantown, WV To whom correspondence should be addressed: Gordon P.
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