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Anissa Bartetzko on Muck Rack

Anissa Bartetzko

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Articles

Investigation of the threonine metabolism of Echinococcus multilocularis: the threonine dehydrogenase as a potential drug target in alveolar echinococcosis

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By Marc Kaethner, Matías Preza, Pascal Zumstein, Anissa Bartetzko
| BioRxiv
Abstract Alveolar echinococcosis (AE) is a severe zoonotic disease caused by the metacestode stage of the fox tapeworm Echinococcus multilocularis. We recently showed that E. multilocularis metacestode vesicles scavenge large amounts of L-threonine from the culture medium that were neither stored nor overused for protein synthesis. This motivated us to study the effect of L-threonine on the parasite and how it is metabolized.
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