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Anja Baresic

As seen in: Nature, The American Journal of Human Genetics
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Articles

Single-cell analysis of the peripheral immune landscape in Parkinson’s disease: insights into dendritic cell and CD4+ T-cell transcriptomics - npj Parkinson's Disease

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By Katarina Mandić, Lidija Cvetko Krajinović, Anja Baresic
| Nature Verified
Abstract Parkinson’s disease (PD) is characterised by α-synuclein aggregation, dopaminergic neuron loss and chronic neuroinflammation. Disruption of the blood-brain barrier enables immune cell infiltration, including dendritic cells (DCs) and CD4+ T-cells, contributing to disease progression.
Open in Who Shared Issue with article?

DNA-binding affinity and specificity determine the phenotypic diversity in BCL11B-related disorders

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By Ivan K. Chinn, Jonathan May, Anu Goenka, Kate Chandler, Jennifer E. Posey, Alexandra Afenjar, Luisa Averdunk, Maria Francesca Bedeschi, Thomas Besnard, Melanie Brugger, Theresa Brunet, Susan Byrne, Valeria Capra, Paúl Cárdenas, Celine Chappe, Hey J. Chong, Benjamin Cogné, Erin Conboy, Heidi Cope, Thomas Courtin, Wallid Deb, Robertino Dilena, Christèle Dubourg, Magdeldin Elgizouli, Erica Fernandes, Kristi Fitzgerald, Silvana Gangi, Muge Gucsavas-Calikoglu, Tobias B. Haack, Maria Iascone, Bertrand Isidor, Jay J. Jin, Dragana Josifova, Ruta Kalinauskiene, Erik-Jan Kamsteeg, Boris Keren, Heike Kölbel, Christian Kubisch, Suzanne Leal, Gholson J. Lyon, Suneeta Madan-Khetarpal, Elaine Marchi, Beatriz Menéndez, Vincenzo Nigro, Sylvie Odent, Renske Oegema, John Pappas, Konrad Platzer, Rachel A. Rabin, Aisha Rekab, Ferruccio Romano, Isabelle Schrauwen, John Short Verified, Richard Sidlow, Jennifer Sullivan, Katalin Szakszon, Queenie Tan, Matias Wagner, Dagmar Wieczorek, Bo Yuan, Nicole Maeding, Dirk Strunk, Amber Begtrup, Siddharth Banka, James R. Lupski, Eva Tolosa, Davor Lessel, Ivana Lessel, Anja Baresic, Rae Brager, Lauren Brick, Jaya K. George-Abraham, Medard Hadonou, Britta Hanker, Irina Hüning, Irma Järvelä, Alexander A.L. Jorge, Elena Kessler, Mariya Kozenko, Alma Kuechler, Juha Leppälä, Sharon M. Luu, Margherita Mancardi, Lakshmi Mehta, Chantal F. Morel, Sue Moyer Harasink, Dayna-Lynn Nevay, Matthew T. Pastore, Yezmin Perilla-Young, Nina Powell-Hamilton, Raissa C. Rezende, Leema Robert, Karin Poths, Jessica Sebastian
| The American Journal of Human Genetics Verified
Keywords BCL11B C2H2-type zinc finger protein recognition code genotype-phenotype correlation type 2 innate lymphoid cells Introduction Proteins containing a Cys2-His2 zinc-finger domain (C2H2-ZnF) constitute the largest class of human transcription factors.1 They act by either repressing or activating the expression of target genes through binding a specific DNA sequence by their tandem and modular C2H2-ZnFs. Each C2H2-ZnF shares a consensus sequence that folds in the presence of zinc (Zn2+)...
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