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Anjelica Miranda on Muck Rack

Anjelica Miranda

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Maf expression in B cells restricts reactive plasmablast and germinal center B cell expansion - Nature Communications

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By Sophie Hillion, Marina Boudigou, Laëtitia Le Pottier, Divi Cornec, Raul Torres, Raúl Torres Verified, Anjelica Miranda
| Nature Verified
Abstract Precise regulation of B cell differentiation is essential for an effective adaptive immune response. Here, we show that B cell development in mice with B cell-specific Maf deletion is unaffected, but marginal zone B cells, germinal centre B cells, and plasmablasts are significantly more frequent in the spleen of naive Maf-deficient mice compared to wild type controls.
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