Ankit Parag Shah

You are already at the latest version Therapy for chronic lymphocytic leukemia (CLL) has evolved dramatically with the introduction of targeted agents, particularly Bruton tyrosine kinase inhibitors (BTKis) and BCL2 inhibitors (BCL2is). This review summarizes contemporary frontline and relapsed/refractory treatment strategies, with an emphasis on molecular risk stratification, combination and triplet regimens, measurable residual disease (MRD)–guided therapy, and time-limited approaches.

You are already at the latest version For decades, artificial intelligence transformed digital domains while the physical world, with its unforgiving dynamics and infinite variability, remained largely beyond reach. That boundary is now dissolving: humanoid robots work full shifts on assembly lines, autonomous vehicles make millions of safety-critical decisions daily, and robotic surgical platforms have performed over twenty million procedures worldwide.

Submitted: 12 January 2026 You are already at the latest version Large language models (LLMs) have significantly advanced artificial intelligence, yet their high com-putational, energy, and privacy costs pose substantial challenges. In contrast, Small Language Models(SLMs), typically with fewer than 15 billion parameters, have emerged as efficient alternatives.