Anling Zhang

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4 DISCUSSION PKN1 correlates with multiple cancers. In prostate cancer, PKN1 enhances the proliferation and migration of prostate cancer cells by regulating the PKN1-WDR5-Kat8 and PKN1-H3T11P-WDR5-H3K4Me3 signalling pathways.5, 27, 28 In pancreatic ductal adenocarcinoma (PDAC), PKN1 acts as a downstream regulator for the FAK/PI3K/AKT signalling pathway, promoting PDAC cell proliferation.29 However, the role of PKN1 in glioma has not been reported.

Loading metrics Open Access Peer-reviewed Research Article Peng Xu , Anling Zhang , Rongcai Jiang, Mingzhe Qiu, Chunsheng Kang, Zhifan Jia, Guangxiu Wang, Lei Han, Xing Fan , Peiyu Pu Peng Xu, Anling Zhang, Rongcai Jiang, Mingzhe Qiu, Chunsheng Kang, Zhifan Jia, Guangxiu Wang, Lei Han, Xing Fan, Peiyu Pu Published: January 21, 2013 https://doi.org/10.1371/journal.pone.0053654 Retraction Concerns have been raised about several results reported in this article [1]: The second and last FACS...