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Introduction Major lower extremity amputations are debilitating, life-altering surgical interventions, most commonly performed as a consequence of peripheral arterial disease and/or diabetes in patients with significant multimorbidity [1, 2]. Outcomes following major lower extremity amputations are often poor, with significant functional and psychosocial debilitation, and 1-year mortality rates can be as high as 48% [2, 3].
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