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John Chalmers on Muck Rack

John Chalmers

Indonesia
As seen in: MSN, MSN Canada, MSN UK, O Globo, Business Insider, Color Research & Application, Daily Mail, HuffPost, MSN South Africa, Nature and
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Articles

A meta-analysis of the long-term effects of antihypertensive therapy on the risk of major cardiovascular disease across 51 randomized trials

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By Qianqian Yang, Zeinab Bidel, Dexter Canoy, Guyu Zeng, William C. Cushman, Anthony Rodgers, Koon K. Teo, Barry Davis, John Chalmers, Carl Pepine, Johan Sundström, Mark Woodward, Milad Nazarzadeh, Kazem Rahimi
| Nature Verified
Abstract Blood pressure (BP)-lowering therapy reduces cardiovascular risk, but whether its proportional benefits increase with longer treatment duration remains unclear. We conducted an individual participant-level data meta-analysis of 51 randomized trials from the Blood Pressure Lowering Treatment Trialistsʼ Collaboration (358,642 participants; median follow-up: 4.2 years).
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Peri‐operative pain management in major lower extremity amputation in vascular Surgery: a UK anaesthetic and vascular surgery Delphi consensus study*

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By Thanapon Ekkunagul, Caitlin Sara MacLeod, John Chalmers, Anna Celnik
| Association of Anaesthetists
Introduction Major lower extremity amputations are debilitating, life-altering surgical interventions, most commonly performed as a consequence of peripheral arterial disease and/or diabetes in patients with significant multimorbidity [1, 2]. Outcomes following major lower extremity amputations are often poor, with significant functional and psychosocial debilitation, and 1-year mortality rates can be as high as 48% [2, 3].
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Hypertension and orthostatic hypertension in 85-year-olds and associations with mortality and cognitive decline in a longitudinal cohort study - Scientific Reports

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By Simon Stahl, Peder af Geijerstam, Magnus Wijkman, Maria M. Johansson, John Chalmers, Katarina Nägga
| Nature Verified
Abstract Hypertension is a risk factor for cardiovascular disease, but the evidence for treatment and blood pressure (BP) targets in the elderly is less robust. Orthostatic hypertension is a potential risk factor for cardiovascular mortality and cognitive decline. All 85-years-olds in Linköping municipality, Sweden, were invited to a prospective birth cohort study including questionnaires, cognitive testing and physical examinations, including supine and orthostatic BP measurements.
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