Alexandria K. Driessen, Anna-Claire Devlin, Fionnuala T. Lundy, S. Lorraine Martin, Gerard P. Sergeant, Stuart B. Mazzone, Lorcan P. McGarvey European Respiratory Journal 2020; DOI: 10.1183/13993003.00758-2020 Abstract Chronic cough can be a troublesome clinical problem. Current thinking is that increased activity and/or enhanced sensitivity of the peripheral and central neural pathways mediates chronic cough via processes similar to those associated with the development of chronic pain.