Anna Concetta Spina on Muck Rack

Anna Concetta Spina

As seen in: Nature, Taylor & Francis Online
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Articles

CXCR4, CXCR7 and PBRM1 are responsible for everolimus and cabozantinib resistance in human renal cancer cells

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By Federica Auletta, Anna Belló, Giuseppina Rea, Maria Cristina Napolitano, Anna Maria Trotta, Daniela Russo, Anna Concetta Spina, Crescenzo D’Alterio, Serena Ascrizzi, Giovanni Luca Scaglione, Pierfrancesco Tassone, Stefania Scala, Caterina Ieranò, Francesca Galdiero, Giuseppe Guardascione, Sara Santagata, Cinzia Vetrei, Gaetana Di Maiolo, Luigi Portella
| Nature Verified
Abstract The mTOR inhibitor everolimus (RAD001), previously used in first-line treatment of metastatic renal cancer (mRCC), is currently reserved for the following lines of therapy. However, many patients eventually develop resistance to RAD001. To shed new light on the mechanism of RAD001 resistance, A498 cells resistant to 1–5–10 µM of RAD001 were developed (A498-RAD 1-5-10).
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Asymmetries run deep: the interplay between cradling bias, face recognition, autistic traits, and personality

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By Linda Semeraro, Paolo Taurisano, Anna Concetta Spina, Giorgia Francesca Scaramuzzi
| Taylor & Francis Online
ABSTRACT Personality traits are linked to a variety of cognitive and socio-emotional factors, including lateralization patterns. Autism, prosopagnosia, and atypical cradling have been associated with altered lateralization and socio-emotional processing. This study explores how autism traits, cradling-side preferences, and face recognition abilities relate to individual personality differences.
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