Introduction Asthma severity is a complex multidimensional entity that is traditionally defined across multiple airway-centric domains, including day-to-day asthma symptoms, treatment needed to control those symptoms, exacerbation frequency, health-care needs, and severity of airflow obstruction.1 The Asthma Severity Scoring System (ASSESS) score,2 developed in the Severe Asthma Research Program, encompasses measures of asthma control, airflow obstruction, treatment need, and health-care...