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Keywords ferroptosis GPX4 Alzheimer’s disease neurodegeneration cell death neuroinflammation spondylometaphyseal dysplasia Sedaghatian type SSMD Introduction The progressive loss of neurons is a recurring feature of neurodegenerative diseases, a diverse group of disorders characterized by cognitive decline, motor impairment, and, in many cases, premature death.1,2,3,4 Although neuronal death is a shared endpoint, each neurodegenerative condition presents with distinct pathological hallmarks,...
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