Annabel Lee on Muck Rack

Annabel Lee

England
As seen in: Medium, MSN, Yahoo Life, Business Insider, Forbes, MSN Malaysia, MSN South Africa, Nature, The Guardian, The Telegraph and
Freelance writer and comms consultant I write about work, parenting, health and wellbeing for places like Insider, Fit+Well and Well+Good

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Articles

I got hooked on Instagram dog-training videos. It sucked the fun out of having a puppy

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By Annabel Lee
| Yahoo Life Verified
It started innocently enough – before bringing home my new puppy, I decided to watch a few videos on Instagram about the best way to help a dog settle in. I wanted to give her – Tallulah, an apricot cockapoo with a perfect white stripe on her nose and forehead – the best start to life, so I followed a handful of dog trainers who seemed to offer common sense advice. Within a week I’d learnt everything from how not to overwhelm the puppy with “too much too soon” to the importance of crate training.
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The one change that worked: I felt like an outsider in my village – until I found a simple way to connect

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By Annabel Lee
| Yahoo Style Canada Verified
‘It started with the PTA’ … Annabel Lee at a school fete.Photograph: Sarah Lee/The Guardian (Photograph: Sarah Lee/The Guardian) I live in a fairly average town in Oxfordshire, and despite having friends and family nearby, I never felt as if I was properly a part of the community. I didn’t feel rooted, or that I knew my neighbours beyond a quick hello. I moved here in my late 20s with my partner and spent a lot of time at home. In my 30s, I got a dog, had children and started working from home.
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Structural mechanism for noncanonical GPCR signaling in the Hedgehog pathway

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By William Steiner, Nathan Iverson, Guibing Liu, Varun Venkatakrishnan, Jian Wu, Tomasz Maciej Stepniewski, Ju-Fen Zhu, Annabel Lee, Isaac Nelson, Daniela Bertinetti, Corvin D. Arveseth, Gerald Tan Verified, Paul Spaltenstein, Jiewei Xu, Ruth Hüttenhain, Michael Kay Verified, Friedrich W. Herberg, Erhu Cao, Jana Selent, Ganesh S. Anand, Susan Taylor, Benjamin Myers, Zachary Michaelson, Jan W. Bröckel, Jessica G. H. Bruystens, Roland L. Dunbrack Jr.
| Nature Verified
Abstract The Hedgehog (Hh) pathway is fundamental to embryogenesis, tissue homeostasis and cancer. Hh signals are transduced through an unusual mechanism; upon agonist-induced phosphorylation, the noncanonical G-protein-coupled receptor (GPCR) Smoothened (SMO) binds the protein kinase A (PKA) catalytic subunit (PKA-C) and physically blocks its enzymatic activity.
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