Anne Barton
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Development of a Complex Methotrexate Adherence Intervention Utilising
Introduction Rheumatoid arthritis (RA) is a chronic disease for which there is no known cure that affects ~1% of the adult population.1 The hallmark of RA is symmetrical joint inflammation which, when left untreated, can lead to joint destruction, disability, multimorbidity and reduced life expectancy by up to 10 years.2 RA treatment is predominantly aimed at controlling joint inflammation and early effective therapy reduces disability, joint damage and mortality.3,4 Conventional Synthetic...
Machine Learning Analysis of Whole‐Blood Transcriptomics Data in Rheumatoid Arthritis Patients Treated with Adalimumab Identifies Predictive Biomarkers of Response
Supporting Information Filename Description art43255-sup-0001-Disclosureform.pdfPDF document, 3.6 MB Disclosure Form art43255-sup-0002-Supinfo.docxWord 2007 document , 1.1 MB Appendix S1: Supporting Information
Genetically Proxied Interleukin‐13 Inhibition Is Associated With Risk of Psoriatic Disease: A Mendelian Randomization Study
INTRODUCTION Inhibitors of the interleukin 13 (IL-13) pathway, such as dupilumab (dual interleukin 4 [IL-4]/IL-13 inhibitor), tralokinumab, and lebrikizumab (pure IL-13 inhibitors), were developed to treat atopic diseases including atopic dermatitis, chronic rhinosinusitis, and asthma.1-4 Musculoskeletal adverse events resembling seronegative spondyloarthritis have been reported after dupilumab initiation, but evidence is limited to case series and spontaneous pharmacovigilance with uncertain...
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