Anne-Laure Barbotin
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Male reproductive phenotype in cystic fibrosis: comparison of existing animal models
Abstract In men, cystic fibrosis (CF) leads to infertility in over 95% of cases, due to early and progressive atresia of the vas deferens, resulting in obstructive azoospermia. The advent of highly effective modulator therapy has enabled more men with CF to consider parenthood, raising important questions regarding the impact of these treatments on male fertility.
Recommendations for Human Sperm Morphology Assessment in 2025: An Expert Review From the French BLEFCO Group
1 Introduction For many years, sperm morphology has routinely been assessed when investigating male infertility and before assisted reproductive techniques (ART). Epidemiological studies comparing fertile men whose partners achieved natural pregnancy and infertile men have demonstrated that sperm morphology was correlated with the chances of natural pregnancy [1-3].
Cystic fibrosis: influence of CFTR variants on epididymal sperm recovery and ICSI results
ArticleArticles in Press105042Open access 1Institut de Biologie de La Reproduction-Spermiologie-CECOS, Hôpital Jeanne de Flandre, CHU Lille, Lille, France 2Univ.
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