Anneliese Krell on Muck Rack

Anneliese Krell

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Articles

MiR‐16‐5p is frequently down‐regulated in astrocytic gliomas and modulates glioma cell proliferation, apoptosis, and response to cytotoxic therapy

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By Nina Stojcheva, Anneliese Krell, Marietta Wolter, Caroline Hertler
| Wiley Online Library Verified
Aims Aberrant expression of microRNAs (miRNAs) is frequent in various cancers including gliomas. We aimed to characterize the role of miR‐16‐5p as a candidate tumour suppressor miRNA in gliomas. Methods Real‐time PCR‐based approaches were used for miRNA and mRNA expression profiling of glioma and non‐neoplastic brain tissues as well as glioma cell lines. Protein levels were determined by Western blotting.
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