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Annie Elong Ngono on Muck Rack

Annie Elong Ngono

As seen in: Nature, Science Magazine, BioRxiv
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Articles

A Zika virus vaccine with E protein fusion loop mutations protects via CD8 + T cells

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By Qin Li, Hsueh-Han Lu, Julia Timis, Manuel D. Montaño, Luke Eder, Pradip Bhandari, Dawid Zyla, Maximilian Bunz, Henry Madany, Erin Maule, Michael Nguyen, Erica Ollmann Saphire, Lakshmanane Premkumar, Annie Elong Ngono, Sujan Shresta, Kantinan Chuensirikulchai
| Nature Verified
Abstract There are currently no effective vaccines against Zika virus (ZIKV). Candidate vaccines target the ZIKV envelope (E) protein, the major target of anti-ZIKV neutralizing antibodies (nAbs). Here we utilized DNA and RNA platforms to compare virus-like particle vaccines with premembrane (prM) and E expressed either in the wild-type form (Z-prM/E-WT) or with fusion loop (FL) mutations (Z-prM/E-FLM), which limit antibody-dependent enhancement of infection.
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Red tape strangles viral surveillance programs

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By Al Ozonoff, Annie Elong Ngono, Robert Frederick
| Science Magazine Verified
Information & Authors Published In Science Volume 386 | Issue 6728 20 December 2024 Article versions Submission history Published in print: 20 December 2024 Permissions Request permissions for this article. Metrics & Citations Article Usage Altmetrics Cite as Red tape strangles viral surveillance programs.Science386,1357-1357(2024).DOI:10.1126/science.ads3461 Export citation Select the format you want to export the citation of this publication.
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Genomic sequencing and neutralizing serological profiles during acute dengue infection: A 2017 cohort study in Nepal

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By Annie Elong Ngono, Sabita Prajapati, Melanie McCauley, Julia Timis
| BioRxiv
Abstract Dengue virus (DENV) is a mosquito borne flavivirus that poses a threat to nearly 50% of the global population. DENV has been endemic in Nepal since 2006; however, little is known about how DENV is evolving or the prevalence of anti DENV immunity within the Nepalese population. To begin to address these gaps, we performed a serologic and genetic study of 49 patients from across Nepal who presented at central hospitals during the 2017 dengue season with suspected DENV infection.
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