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Enantioselective Miyaura Reaction by Desymmetrizing C(sp2)–B Cross‐Coupling of 1,1′‐Biaryl‐2,6‐diyl Bis(nonaflates)
Arylboronic acids and arylboronate esters are central to synthetic organic chemistry, especially due the enormous success of the Suzuki–Miyaura cross-coupling[1, 2] with applications in academic and industrial settings.[3-5] Consequently, extensive efforts have been devoted to develop reliable methods for the preparation of those boron pronucleophiles.
Dynamic Kinetic C(sp2)-Si Cross-Coupling with Si-B Reagents for the Atroposelective Construction of Unsymmetrical Heterobiaryls
Introduction Click to copy section linkSection link copied! Silicon chemistry is an integral part of synthesis and catalysis. (1) In this context, transition-metal-catalyzed C(sp2)–Si cross-coupling (2,3) and, more recently, cross-electrophile coupling (4,5) (XEC) of a broad variety of prefunctionalized arenes have emerged as viable strategies for the synthesis aryl-substituted silanes.
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