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Articles by Anthony desantis
Effects of chemokine (C-C motif) receptor 2 and 3 antagonists in rat models of hemorrhagic shock
Series 3: Redosing of INCB3284 reduces fluid requirements and prevents hemodynamic decompensation after a 60 min hemorrhagic shock period The half-life of INCB3284 has been reported to be 168 min in rats [15].
Class A G protein‐coupled receptors assemble into functional higher‐order hetero‐oligomers
Editor's Choice Xianlong Gao, Department of Surgery, Morsani College of Medicine, University of South Florida, Tampa, FL, USA Search for more papers by this author Garrett A. Enten, Department of Surgery, Morsani College of Medicine, University of South Florida, Tampa, FL, USA Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA Search for more papers by this author Anthony J.
Regulation of the thrombin/protease-activated receptor 1 axis by chemokine (CXC motif) receptor 4
Xianlong Gao1‡, You-Hong Cheng2‡, Garrett A. Enten1,3, Anthony J.
Regulation of the thrombin/protease-activated receptor 1 axis by chemokine (C-X-C motif) receptor 4
Abstract The chemokine receptor CXCR4, a G protein-coupled receptor (GPCR) capable of heteromerizing with other GPCRs, is involved in many processes including immune responses, hematopoiesis and organogenesis. Evidence suggests that CXCR4 activation reduces thrombin/protease activated receptor 1 (PAR1)-induced impairment of endothelial barrier function. However, the mechanisms underlying cross-talk between CXCR4 and PAR1 are not well understood.
Odin's messengers: Hugin and Munin.
Hugin and Munin (pronounced “HOO-gin” and “MOO-nin”; Old Norse Huginn and Muninn, the meaning of which will be discussed below) are two ravens in Norse mythology who are helping spirits of the god Odin. According to the medieval Icelandic historian Snorri Sturluson. Two ravens sit on his (Odin’s) shoulders and whisper all the news which they see and hear into his ear; they are called Huginn and Muninn.
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